Clinical Chemistry Blog Notes 05

1. False

2. False

3. True

4. False



5. 10-12 hours

6. intravenous solution

7. arginine

8. time intervals

9. GH

10. Increase



CASE:

1. All of the following values will have an increase results in stimulation tests. Since the test stimulates the particular gland to produce more hormone.

2. Hypothyroidism

1. An increase in the amount of a particular hormone would mean an abnormal result.

2. Stimulation Test could be a confirmatory test for Hypothyroidism or Hyperthyroidism.

3. Blood Samples are drawn in time intervals to make sure that the gland have been stimulated.

4. Stimulation Test is only for Growth Hormone.

The patient should have fasted for (5)_________________. Then the blood is drawn after. With an close medical supervision the patient will be given an (6)___________________ of insulin or (7)_________________. Samples are drawn at (8)__________________, wherein the physician would be able to check if the gland had been stimulated. (9) __________ levels are tested to see if the pituitary gland had been stimulated. An (10)________________ in results would be the normal results.

A 45 year old man with the following results

GH: -1.8 ng/ml

T3: 3micg/dl

T4: 0.4 micg/ml

TSH: 6 IU/L

Reference Values:

GH - 0-3 ng/ml

TSH - 0.4 -4.8 mIU/L

T3 - 4.4-12.5 micg/dL

T4 - 1.95 - 9.9 micg/ml

He went to the physician for a routine check-up. The Physician ordered a stimulation Test.

What would be the expected result for the following (increase or decrease):

a. GH

b. TSH

c. T3

d. T4

What would be the diagnosis? ___________________

Picture taken from:

Simulation tests are procedures that could have an affect in the production of a certain hormone or as such. It could also determine if the particular gland is serving its purpose. This technique will enhance or "stimulate" the exact gland, helping the physician to detect and understand if hormones are being secreted and produced in the average amount.

In the Growth Inhibiting hormone, the stimulation test detects if the gland had secreted enough hormones that could be an aid in the diagnosis of some diseases such as hypothyroidism and hyperthyroidism.

In this particular test, the patient must have fasted for 10-12 hours. Then, a sample of blood is drawn after. Then, under close medical supervision, you will be given intravenous solution of insulin or arginine. Blood samples are then drawn at timed intervals, and GH levels are tested in each to see if your pituitary gland was stimulated by the insulin (or arginine) to produce expected levels of GH.